Could be any media from books, games, etc. not just film and tv.
I myself had this idea for a parody of The Boys that showed how screwed a world where superheroes are mostly degenerates would be if faced with actual supervillains.
Like I was thinking villains from DC, Marvel, and outside those two like My Hero Academia, Powerpuff Girls, Teenage Mutant Ninja Turtles, Darkwing Duck, Ben 10, Danny Phantom, etc. end up in the world of The Boys and end up running amok.
Like it could start out like typical stuff you'd see in The Boys only for Vilgax to show up and give off the feeling that something's not right, then he murders Homelander and everything goes to hell, especially since most supes haven' dealt with the likes of Negaduck, HIM, etc.
If Garth Ennis saw the Boys universe be devastated by supervillains, he'd be pissing and shidding himself since it's basically a problem that only superheroes (Which he hates aside from a few. Most notably, The Punisher) could deal with.